Information
on QA Scheme: Early Human Embryology QAP-2012
Comment = A series of images of human cleavage stage embryos for QC/QA purposes. The images may be either animated gif files, static multiple embryo images or 15 second videos in either avi,mpg or mov formats. The primary question used for quality assessments, the QAP question, is the same calculated embryo scrore parameter [ESP]. This allows for the assessment to be based upon the common criteria embryologists used in their daily embryo grading. The sum of each paramter leads to a calculated value that is submitted for assessment and comparison. The multiple images (4 per page) is used to assess comparative judgements for both transfer and for freezing. A text based summary has been included allowing participants to review how others describe and guage embryos. While the replies to all questions can be probed from conformity, the QAP question forms the basis for internal quality control and for external comparison for both each staff member and for the clinic overall.
Number of enrollments =325 [* This indicates only
the number of enrollments. Not all participants will have completed
the scheme]
List of QA Issues (or Instalments)
Code
Title
Available
from
HEE2012.01-1
Single Human Embryo
1/1/2012
HEE2012.02-1
Single Human Embryo
1/2/2012
HEE2012.03-1
Single Day 2 Embryo
1/3/2012
HEE2012.03-2
Three Day 2 human embryos
1/3/2012
HEE2012.04-1
Single Day 3 Embryo
1/4/2012
HEE2012.05-1
Day 2 embryo at 44 hrs
1/5/2012
HEE2012.06-1
Single Day 2 Embryo
1/6/2012
HEE2012.06-2
Two Day 3 Human Embryo
1/6/2012
HEE2012.07-1
Single Day 3 Embryo
1/7/2012
HEE2012.08-1
Single Day 3 Embryo
1/8/2012
HEE2012.09-1
Single Day 3 Embryo
1/9/2012
HEE2012.09-2
Four Day 2 Human Embryo
1/9/2012
HEE2012.10-1
Single Day 3 Embryo
1/10/2012
HEE2012.11-1
Single Day 2 Embryo
1/11/2012
HEE2012.12-1
Single Day 3 Embryo
1/12/2012
HEE2012.12-2
Four Human Embryo
1/12/2012
List
of Questions asked for QA Scheme:Early Human Embryology QAP-2012
Detailed
Information on Question: What is the embryo score for this embryo
Status
This is the
KEY QAP Question for the Scheme
Type
Calculation Outcome
Order
Question
Options
1
The calculated embryo score is:
Title
Embryo Score-Ver 1
Comment
This score calculates the number of cells *[cleavage+ Fragmentation+cell size+compaction]
This
is a calculated Question. It requires a number of other questions
to be completed. The answer to these questions have each been weighted
(see below). The value submitted for each question is then compiled
as detailed below to provide a SCORE usually out of 100. The higher
the score usually indicates a better quality. The score is an arbitary
one and has been generated within QAPonline to allow all the parameters
embodies in the questions to be assess.
Order
Question
Calculation
Summation
1
How even are the size of the blastomeres.
Value
*1
+
2
What is the % fragmentation on this embryo
Value
(100-x)/100100
+
3
Is the rate of cleavage normal?
Value
*1
+
4
Describe the degree of compaction.
Value
*1
+
5
How many cells are in the embryo
Value
*1
*
1
How even are the size of the blastomeres.
Order
Option
Value
Max
value
1
The blastomeres appear of equal size
1
1
2
The blastomeres differ only marginally in size
0.75
1
3
The blastomeres differ significantly in size
0.5
1
5
How many cells are in the embryo
Order
Option
Value
Max
value
1
The number of cells are
0
25
2
What is the % fragmentation on this embryo
Order
Option
Value
Max
value
1
The % fragmentation is:
0
1
3
Is the rate of cleavage normal?
Order
Option
Value
Max
value
1
YES, this embryo is normal.
1
1
2
No - this embryo has cleaved or developed faster than expected.
0.75
1
3
No, the embryo is delayed.
0.5
1
4
No, the embryo has arrested or significantly delayed.
KEY QAP Question for the Scheme