Mammalian sperm contain two factors for calcium release and egg activation: Phospholipase C zeta and a cryptic activating factor
Mammalian sperm induce a series of calcium oscillations in the egg at fertilization responsible for triggering the transition to a 1-cell embryo and for blocking polyspermy. Phospholipase C (PLC) zeta is a sperm-specific protein capable of mimicking these fertilization calcium changes through its ability to generate inositol trisphosphate. Here I comment on two recent landmark studies that report on knockout of PLC zeta in mice.
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No problem- Goto the IVFCPD education modules and select those of interest. Each module with learning objectives, review and journal links, question for completion and proof of participation and online documentation. Consider these to be like an in-service program. Ask your staff to complete the CPD exercises as part of their training program.
Each module should consume ~30 minutes of self directed learning.
May be of interest to IVF Nursing, counsellors, medical and laboratory staff.
Ask your clinical management or pharmaceutical representative to support you enrollment.