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Association Between Assisted Reproductive Technology Conception and Autism in California, 19972007
Results. In the full population, the incidence of diagnosed autism was twice as high for ART as non-ART births. The association was diminished by excluding mothers unlikely to use ART: adjustment for demographic and adverse prenatal and perinatal outcomes reduced the association substantially, although statistical significance persisted for mothers aged 20 to 34 years.
ajph.aphapublications.org/doi/10.2105/AJPH.2014.302383
181. Fewer multiple births could reduce autism risk in ART children [Forum/Discussion]
from: Administrator (office@fertaid.com), Australia on 22/03/2015 8:15:41 PM Profession:
Comment: In a large and quite worrying study, the likelihood of an IVF child developing autism is TWICE that of non IVF children and linked to multiple pregnancy.
Submission: This is a worrisome study in that is it derived from a large cross-linked analysis showing something that may other wise have been missed. Autism is a post delivery issue that may well pass unnoticed to normal reviews. From what I understand from the report, single embryo transfers were not related to autism but multiple pregnancy and birth complications were. While such studies need to be confirmed in many other reviews, surely this alone is an argument for not risking multiple pregnancy by transferring more than one embryo. This may lead to more day 5 transfers and FETs but may result in lower pregnancy rates. This may be better than the thought of causing even one case of autism. One does not have to think very hard on this issue to realise that continued multiple embryo transfers place the clinic to future risk of litigation unless the risks are clearly explained to clients.
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