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Trends in Use of and Reproductive Outcomes Associated With Intracytoplasmic Sperm Injection
Conclusions and Relevance Among fresh IVF cycles in the United States, ICSI use increased from 36.4% in 1996 to 76.2% in 2012, with the largest relative increase among cycles without male factor infertility. Compared with conventional IVF, ICSI use was not associated with improved postfertilization reproductive outcomes, irrespective of male factor infertility diagnosis.
jama.jamanetwork.com/article.aspx?articleid=2091303
113. Trends in Use of and Reproductive Outcomes Associated With Intracytoplasmic Sperm Injection [Forum/Discussion]
from: Administrator (office@fertaid.com), Australia on 24/01/2015 11:16:22 AM Profession:
Comment: There has been more than a doubling in the use of ICSI in the USA between 1992 and 2012 mainly for couples without a male factor competent.
Submission: The authors data suggested indirectly than this may have been associated with a decrease in cycle cancellation due to failed fertilisation but also a slight decrease in implantation rates and live births. The authors had no information to explain the increase nor did they express concern in this trend. It does however mean both an increase in the cost of ART by couples since all ICSI will attract an ICSI fee and an increase in the workload of embryology staff and more stress on embryo culture systems since an ICSI cycle requires increased handling of gametes and embryos.
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